Urine sugar 4 + may be caused by diabetes, hyperthyroidism and other disease factors, may also be caused by physiological factors. Physiological factors can return to normal, disease factors caused by standardized treatment can also be restored. Normal people’s urine sugar is very little, the general method of detection can not be found, usually negative, when there is a urine sugar 4 + considered to be caused by diabetes, hyperthyroidism and other disease factors. Diabetic patients can be treated with oral hypoglycemic drugs such as metformin or insulin injections to maintain blood glucose within a reasonable range, and a positive urine glucose may also return to normal. Patients with hyperthyroidism can be treated with antithyroid medications such as methimazole or iodine radiation therapy or surgery to maintain thyroid hormones within reasonable ranges, and positive urine glucose can return. In addition, eating large amounts of carbohydrates or suddenly eating a full meal after a long period of starvation may also cause a temporary increase in urine glucose, which can be recovered on its own. Patients with 4+ urinary glucose can go to the hospital and consult a professional doctor for a clear diagnosis and timely treatment under the doctor’s guidance.