Rectal cancer is prone to bone metastasis, and the current treatment is based on surgery and chemotherapy of the primary tumor. Combined with the current situation of the patient, the following are recommended: 1. change the chemotherapy regimen and perform chemotherapy treatment for rectal cancer again 2. give bisphosphonates to inhibit bone destruction 3. analgesia and other symptomatic treatment 4. spinal lesions can be treated with radiotherapy 5. traditional Chinese medicine and immunotherapy