At present, besides cardiovascular diseases, cancer is the most dangerous scourge that affects human health. One-fourth of the causes of death in China is cancer, and one-fourth of the causes of death from cancer is stomach cancer. Among the deaths from malignant tumors of the digestive system, about half of them are caused by stomach cancer. There are more than 1 million new cases of gastric cancer worldwide every year. China accounts for 42% of them, and about 800,000 deaths, of which China accounts for about 35%, which shows that China is one of the countries with the highest incidence and mortality rate of gastric cancer. Its incidence rate increases significantly with age, with the peak age ranging from 50 to 80 years old, but has been showing a trend of rejuvenation year by year, and the proportion of patients aged 19-35 years old in gastric cancer has increased from 1.7% to the current 3.3% in 40 years. The high incidence areas of gastric cancer in China are Shandong, Henan, Liaoning, Fujian, Gansu, Qinghai, Ningxia, Jilin, Jiangsu, Shanghai, etc. Some friends ask what is the treatment effect of gastric cancer? In fact, the efficacy of gastric cancer is closely related to the early and late stage of the disease and the diagnosis and treatment methods and means. 90% of patients with early stage gastric cancer can survive for more than 5 years or be cured after adequate treatment, while the 5-year survival rate of patients with very advanced gastric cancer is less than 5% after treatment. Therefore, early detection is the key to improve the efficacy and survival rate. Unfortunately, only less than 10% of gastric cancer patients in China are in early stage when diagnosed, compared with about 60% in Japan, which is a big gap; mainly because Japan insists on regular gastroscopy, while most patients in China seek medical treatment for discomfort, and most gastric cancer patients have symptoms only in the middle and late stages. Therefore, regular gastroscopy and other examinations for people at high risk of gastric cancer are effective means to detect early gastric cancer. High-risk people refer to those who have high risk of stomach cancer: (1) precancerous lesions: precancerous lesions refer to benign diseases with cancer tendency, such as: (1) chronic atrophic gastritis, with cancer rate up to 10%; (2) chronic gastric ulcer, with cancer rate less than 3%; (3) gastric polyps, with diameter >2cm, multiple and wider base, with high cancer rate; (4) partial gastrectomy, with cancer rate of residual stomach up to 0.3%-10 (5) other precancerous lesions, such as giant gastric mucosal hypertrophy, warty gastritis, etc.; (6) gastroscopic biopsy pathological types: ① heterogeneous hyperplasia, also called atypical hyperplasia, caused by chronic inflammation, such as the development of severe atypical hyperplasia can be considered as precancerous lesions or even early cancer; ② gastric interstitial changes have more chances of carcinogenesis; ③ colonic intestinal chemosis is closely related to the occurrence of gastric cancer. 2, poor dietary habits: such as irregular diet, fast eating, high salt/hot food, pickled, smoked and overnight dishes with high content of carcinogenic nitrite, red meat with barbecue, frequent consumption of moldy food and less fresh vegetables, etc. 3.Long-term alcoholism and smoking: alcohol can change the mucous membrane cells and cause cancer. Smoking is also a strong risk factor for stomach cancer. 4.Family history of gastric cancer or esophageal cancer: the incidence of gastric cancer among patients’ family members is 2-3 times higher than that of normal population. 5.Long-term poor psychological status: such as depression, sadness, loneliness, depression, disgust, self-blame, guilt. 6.Some special occupations: those who are exposed to sulfuric acid dust and mist, lead, asbestos, herbicides and metal industry workers have significantly higher risk of gastric cancer. 7.Geology and water quality containing harmful substances: areas with geology of volcanic rocks, high peat and deep large faults have small Ca/SO4 ratio in water and high content of nickel, selenium and cobalt. Selenium and cobalt can also cause gastric damage, and nickel can promote the carcinogenic effect of 3,4 benzo(a)pyrene. 8. Helicobacter pylori (Hp) infection: Some studies say that about half of gastric cancer is related to H. pylori infection. About 60% of the national population is infected with the bacteria, but only 0.03% of the population suffers from gastric cancer. Early gastric cancer: More than 70% of early gastric cancers are asymptomatic, and those with symptoms are generally atypical. Mild discomfort in the upper abdomen is the most common initial symptom, similar to indigestion or gastritis. Progressive gastric cancer: No previous history of gastric disease, but recently unexplained epigastric discomfort or pain; or previous history of gastric ulcer, and recently the frequency and degree of epigastric pain has increased. 1. Upper abdominal fullness is often the earliest symptom of progressive gastric cancer in the elderly, sometimes accompanied by belching, acid reflux and vomiting. If the cancer is located in the cardia, the patient may feel that the food is not smooth; if the cancer is located in the pylorus and there is obstruction, the patient may vomit the rotten overnight food. 2.Loss of appetite, emaciation and weakness: According to statistics, about 50% of the elderly patients have obvious loss of appetite, increasing emaciation and weakness, and 40%-60% of the patients seek medical treatment for emaciation. 3. Gastrointestinal bleeding: vomiting blood (10%), black stool (35%) and persistent fecal occult blood (60-80%) (small amount, no blood to the naked eye but detectable by laboratory test) are positive. Regular medical checkups for people at high risk of gastric cancer should be conducted as soon as there is unidentified upper abdominal discomfort or pain, belching, acid reflux and vomiting.