Coughing in bed can have a variety of causes, which need to be identified and treated. Common causes include left heart failure, cough variant asthma and reflux esophagitis, etc. Treatment includes general therapy and medication. 1. Left heart failure: It is caused by the decline of heart function that leads to pulmonary stasis. Lung stasis is aggravated at night when lying down, so it leads to a strong cough at night. This cough is sometimes relieved by being forced to sit up. It can be relieved by using diuretics and cardiotonic agents such as furosemide and digoxin. 2. Cough variant asthma: belongs to a type of asthma, with irritating dry cough at night as the main manifestation, especially when smelling irritating odor is more obvious. Night cough caused by this kind of disease can be used under the guidance of the doctor inhalation budesonide, salmeterol and other drugs. 3. Reflux esophagitis: mainly related to the reflux of gastric juice when lying down, its symptoms mainly include burning sensation or pain behind the sternum, reflux, difficulty in swallowing, chest pain and other symptoms. Usually, we should eat a light diet, rich in nutrients, and can use drugs such as cisapride. There are other reasons for coughing once you sleep, and it is recommended that you visit the hospital in time to find out the cause. The above drugs should be used under the guidance of a doctor.