The general management of right papillary thyroid cancer left nodule is based on surgical management, supplemented by postoperative endocrine replacement, radionuclide and other treatments. According to the specific situation, it can also be supplemented with radiation therapy, targeted therapy. The details are as follows: 1. Surgery: for patients with cancerous lesions in the gland and no enlarged lymph nodes in the neck, lobectomy plus buccal resection or total/near-total thyroidectomy can be performed. If there are enlarged lymph nodes, lymph node dissection should be performed in the corresponding area. 2. Pharmacological endocrine replacement therapy: due to insufficient secretion of thyroxine after the operation, it is necessary to take medication for endocrine replacement therapy, commonly used medication is levothyroxine tablets. 3. Targeted therapy: for advanced iodine-refractory papillary carcinoma patients with symptoms, targeted therapy drugs such as sorafenib and levatinib can be used for treatment. 4. Iodine-131 therapy: the rays emitted by iodine-131 have the biological effect of ionizing radiation, which can destroy the residual thyroid tissues and cancer cells, and it has good curative effect on the metastatic lesions of thyroid cancer.