Generally speaking, perianal thrombosis is more dangerous and heavy. Perianal thrombus belongs to a kind of hemorrhoids, generally due to drinking, eating spicy, constipation, toilet squatting, sitting for a long time and other reasons to the perianal subcutaneous blood pressure increases, excessive expansion rupture and cause; the harm is mainly the following three points. 1. Infection: if you do not pay attention to perianal thrombus will bring a lot of harm, first of all, if the perianal thrombus occurs inlaid, there will be varying degrees of infection, if the treatment is not timely, localized infection of the anus can be spread to the surrounding area, resulting in perianal abscess or rectal fossa abscess, and even the infection can be reached through the portal vein to the liver area, the formation of liver abscesses. 2. Necrosis: secondly, after the perianal thrombus becomes embedded, a series of pathophysiological changes occur, metabolic products accumulate, aggravating anal edema, leading to more serious hemorrhoidal embeddedness, until finally necrosis occurs. 3. induced cardiovascular disease: for middle-aged and elderly people if the defecation force is too violent will lead to accelerated heart rate, blood vessel congestion, and even cause cerebral blood vessel rupture, causing cerebral hemorrhage or cerebral infarction; if the thrombosed hemorrhoids embedded serious, but also can be induced angina pectoris. Therefore, if you find the perianal discomfort is obvious, you should consult a doctor in a timely manner, it is recommended to go to a regular hospital, improve the examination, a clear diagnosis, and follow the doctor’s instructions for treatment.