The four-dose rabies vaccine is given as two injections on the day of exposure and one on day 7 and one on day 21, for a total of four injections. Compared to the traditional 5-dose vaccination method, the 4-dose vaccination method has a shorter total duration and is able to produce antibodies earlier, and is now trending to replace the 5-dose vaccination method. However, the 4-dose vaccination method may aggravate the occurrence of adverse reactions because the rabies vaccine is an inactivated rabies virus that stimulates the body to produce antibodies after entering the body, and some patients, especially children, may experience adverse reactions such as fever, rash, malaise, nausea and vomiting after vaccination. Therefore, the specific method of injection depends on the time needs of the patient and the specific situation. After vaccination, you must not drink alcohol, coffee, strong tea and spicy and stimulating food, and avoid strenuous exercise.