The swelling of one thigh is obvious: 1, it may be due to excessive fatigue, which leads to obstruction of blood circulation in the lower limbs, resulting in the symptoms of swelling of one thigh, which will generally subside after rest. 2, obesity can also lead to the thickness of the two limbs are not the same. 3, there are also people who have seasonal swelling. 4, patients with cardiac insufficiency will also have the symptoms of swelling of one thigh. 5, tumor compression The symptoms of swollen thighs can be caused by poor venous return, poor kidney function, and cirrhosis. 6. Lower limb vein thrombosis can lead to swelling of the affected thighs, so be sure to go to a regular hospital and improve the vascular ultrasound of the lower limbs for a clear diagnosis. 7. It may be a local problem of the limb, such as having been traumatized. If there are no obvious positive signs in the detailed examination, it may be considered more likely to be idiopathic edema, which may also be caused by local lesions. Therefore, if the swelling of one thigh is not relieved by bed rest and elevation of the affected limb within a short period of time, it is important to go to a regular hospital in a timely manner and not to delay the condition.