Early clinical manifestations of gout include swollen and painful joints, gout stones, renal colic, urinary difficulties and so on. 1. Joint swelling and pain: patients mostly feel joint pain at midnight or early in the morning, most commonly in the unilateral 1st metatarsophalangeal joints, the affected joints in a few hours of redness, swelling, heat, pain and dysfunction, patients can take colchicine, non-steroidal anti-inflammatory drugs, such as etoricoxib to alleviate the symptoms, the occurrence of self-limiting, most of them can be relieved within 2 weeks. 2. Renal colic, dysuria: patients may have renal colic, dysuria, hematuria, hydronephrosis and other symptoms due to uric acid stones. 3. Gout stone: gout stone is a characteristic clinical manifestation of gout, the typical site in the auricle, but also common around the joints, as well as the eagle’s beak, Achilles tendon, patellar bursa and other places. When suffering from gout, it is recommended to go to the rheumatology and immunology department of the regular hospital in time, and follow the doctor’s instructions for standardized treatment.