If a middle-aged or elderly patient has worms crawling on his head and is persistent, with a past history of hypertension, diabetes and obesity risk factors, he should go to the hospital for a cranial magnetic resonance examination to find out if there is an infarction in the head, because some of them, such as thalamic infarction, can cause abnormal sensations in the patient and a feeling of worms crawling. At this time, the main treatment for cerebral infarction is to give anti-platelet aggregation, nerve nutrition or symptomatic treatment. 2. If the patient is young, there are worms crawling when sleeping, accompanied by emotional agitation, emotional instability and sleep disorders, there is also a feeling of worms crawling on the body or numbness and pain. This time, consider the possible functional factors, need to do the anxiety and depression scale assessment, to determine whether the patient has the performance of somatization disorder.