Symptoms of gram-negative diplococcus positive are purulent discharge from the urethra, tingling and burning in the urine, swelling of the lower body, frequent urination, urinary urgency, and vulvar itching, and in severe cases, fever. Gram-negative diplococcus refers to gonococcus, which is a relatively common purulent bacteria, the only host is the human urethra and vaginal mucosa. Once infected, it can lead to gonococcal urethritis or gonorrhea, which is a relatively common sexually transmitted disease. Symptoms of Gram-negative diplococcus-positive bacteria may include urinary urgency, frequent urination, painful urination, pus overflow from the urethra, and redness and swelling of the glans in men, and in women. Urgency, frequent urination, painful urination, purulent leukorrhea, and vulvar itching may also occur. In severe cases, an elevated temperature and fever may occur. The main way of transmission is contact with contaminated clothing or sexual contact. It can be treated with intravenous ceftriaxone combined with levofloxacin under the guidance of a doctor, and vancomycin can be used in conjunction with it if resistance develops. The above symptoms, it is recommended to go to the hospital in a timely manner to standardize the treatment, in the treatment at the same time, you also need to check the partner treatment, to avoid cross-infection.