Uneven echogenicity of the thyroid ultrasound means that the thyroid gland is not uniformly involved throughout the thyroid gland. A. It may be an adenoma of the thyroid gland, involving unilateral or unilateral and bilateral portions of the thyroid tissue. 2. It may be an inflammation of the thyroid gland, but not subacute thyroiditis, which involves the entire thyroid gland uniformly, or it may be an acute inflammation of the thyroid gland involving one side of the thyroid gland. The ultrasound may also show echogenic heterogeneity, the aspect ratio of the cancer area is greater than one, the blood flow is uneven, the border is irregular, and sand-like calcifications are combined. It should be combined with thyroid ECT and thyroid function tests to further determine which disease is causing the problem.