High cholesterol may be due to problems in the liver or other causes such as primary cholesterol elevation and hypothyroidism. The liver is the place where cholesterol is metabolized and recirculated. When liver function is impaired due to tumors, infections, cirrhosis, etc., elevated cholesterol can appear. However, elevated cholesterol is not necessarily due to liver problems. Among the people with elevated cholesterol, primary cholesterol elevation accounts for most of them, which is often caused by the interaction between genetic defects and environmental factors, not because of the problem of the body organs with elevated blood cholesterol phenomenon. In addition, there are other diseases that cause secondary cholesterol elevation, such as hypothyroidism, Cushing’s syndrome, nephrotic syndrome, etc., or elevated cholesterol caused by certain medications such as diuretics and glucocorticoids. There are many reasons for high cholesterol, patients should go to the hospital in time, to clarify the cause of the disease and then give targeted treatment.