Prickly heat on the buttocks can usually be treated by keeping the skin dry, topical medication and oral medication. 1. Keep the skin dry and cool: prickly heat is mainly caused by the blockage of sweat ducts in a hot and humid environment. Generally, you can use fans and air-conditioners to cool down the body and keep the skin dry and fresh, which will help to speed up the receding of prickly heat. 2. Topical medication: Topical medication usually focuses on cooling and relieving itching, commonly used medications include anti-itch lotions such as peppermint glycerine lotion and ichthyol glycerine lotion, anti-itch powders such as prickly heat powder and Huanglian pouncing powder, etc. Hormonal creams such as triamcinolone acetate urea cream and hydrocortisone cream can also be used. 3. Oral medication: If the patient has severe itching at the lesions, antihistamines such as loratadine tablets and cetirizine hydrochloride tablets can be taken at the same time to relieve the discomfort if necessary. The above drugs need to be used under the guidance of a doctor, do not self-medication, so as not to cause adverse consequences.