Bleeding spots can disappear in 1 to 2 weeks after effective treatment of leukemia. Bleeding spots in leukemia are mainly caused by thrombocytopenia. After standardized treatment, the condition is effectively controlled, and the bleeding spots can usually disappear in 1 to 2 weeks. Without standardized treatment, the bleeding spots will be progressively aggravated and will not disappear. Different types of leukemia should be treated with different treatment plans, such as chronic lymphocytic leukemia, which can be treated with chemotherapy with drugs such as ibrutinib. When leukemia patients undergo chemotherapy or bone marrow transplantation and other treatments, hematopoietic function is gradually restored, platelet count gradually rises, and the bleeding spots on the body are able to disappear. Leukemia should go to the hospital in time, and the doctor will choose the appropriate treatment plan according to the condition.