Coffee spot birthmark is a kind of pigmentation patch, according to the characteristics of the birthmark and the different parts of the growth, there can be different treatment methods. If the birthmark of coffee spot grows in the trunk, the border is unclear or the color is light, the birthmark does not affect health, but because the coffee spot will not subside by itself, and when it is bigger, there may be the presence of neurofibroma, so it should be and seek medical treatment, after the doctor’s assessment can be temporarily without treatment, but need to pay attention to not use the nails for repeated scratching and stimulation, to prevent the cause of infectious dermatitis, pay attention to observation. When the color of the birthmark is darker, you can choose to use medication, including the external use of ointment with bleaching function, such as azelaic acid cream or thousand white hydroquinone cream, also can choose to take oral vitamin C or glutathione and so on for treatment, but the effect of medication is generally poorer, and the time is longer. When the border of the birthmark is clearer and the color is deeper, laser treatment such as fractional laser or excimer laser can be carried out, and at the same time with oral medication, generally after the scabs produced by the laser fall off, the pigment can be basically subsided. Usually, laser treatment is more effective, but recurrence may occur, and multiple treatments are required, while sun protection should be strengthened during the treatment period. For single cafe-au-lait birthmarks that grow on the face, they can also be treated by surgery, but surgery carries certain risks and may leave scars.