According to TCM theory, autoimmune hemolytic anemia is characterized by deficiency of Yang in the middle, deficiency of cold in the spleen and stomach, and loss of blood through Yang deficiency. The treatment is to tonify Qi, strengthen the spleen, and warm the middle of the body to take in blood. Radix et Rhizoma rehmanniae, Radix Codonopsis pilosulae and Radix Astragali are all herbal immune enhancers, which can enhance and regulate the immune function of the body, stimulate the hematopoietic function of the bone marrow, improve the body’s ability to resist disease, and promote specific humoral immunity. Zi He Che is a human cell coat and has the function of a great tonic for essence and blood. Bone marrow of beef is full of marrow and warm in nature. In accordance with the principle of “Nei Jing”: “those who are deficient in essence are tonified with taste”, the use of blood and flesh with warming and strengthening the spleen can fill the essence and replenish the qi and blood, and the essence is full of blood. The herbal medicine is made up of 10g of Radix et Rhizoma Polygonati, 30g of Radix Codonopsis Pilosulae, 15g of Atractylodes Macrocephala, 6g of Radix Ginger, 30g of Radix Astragali, 10g of Radix Angelicae Sinensis and 15g of Radix Ziziphiopogonis. 800ml of water is decocted to 200ml, and 400ml of water is decocted to 200ml for the second decoction, and the two juices are mixed and divided into 2 times/day. Take 25 doses for 1 course of treatment, rest for 5 days and then proceed to the second course of treatment. After 2 courses of treatment, the symptoms improve and the blood picture improves as effective, otherwise it is not effective. For those with bleeding symptoms, add medicine to warm the blood, stop bleeding and dispel blood stasis, and use mugwort, lateral cypress leaf, Tian Qi and Dan Shen according to the site of bleeding.