After blisters are abraded on toes, relief can usually be given in the form of general treatment, local puncture, and medication intervention. 1. General treatment: If the blisters rubbed out from the toes are small, most of them do not need special treatment and will be gradually absorbed and metabolized by the body over time. 2. Local puncture: If the blisters are large and accompanied by pain and swelling, you need to go to the hospital, and then a professional physician will perform a puncture to extract the liquid inside and give iodine povidone and saline disinfection treatment. 3. Pharmacological intervention: local blisters phenomenon if infection has occurred, it is necessary to add oral amoxicillin, cephalosporin medication to prevent the worsening of the symptoms of infection. It is recommended that patients with blisters on their toes should combine their own situation and follow the doctor’s instructions to give the corresponding treatment. Pay attention to the wound do not touch water, avoid infection, wear comfortable loose shoes.