There is no so-called “best treatment” for rheumatoid arthritis in the elderly. Individualized treatment plan should be formulated according to the patient’s condition, and the main treatment methods are anti-infection and anti-rheumatic drug treatment. Rheumatoid arthritis is a reactive disease caused by infection of group A beta-hemolytic streptococcus, which can occur at any age without gender difference, and manifests itself as localized redness, swelling, heat, pain, and limitation of activity in the joints, which can be cured but is prone to recurrent episodes, and is currently treated with anti-infective and anti-rheumatic drugs. Commonly used anti-infective drugs are benzylpenicillin, etc. Patients who are allergic to penicillins can also be treated with cephalosporins, erythromycin, roxithromycin, etc. Anti-rheumatic drugs such as aspirin, dexamethasone, hydrocortisone, etc. can help to eliminate the inflammation of the joints and alleviate the joint pain symptoms, etc. The drugs should be used under the supervision of a physician. Drugs need to be used under the guidance of a physician, it is recommended that patients with rheumatoid arthritis go to the rheumatology and immunology department of a regular hospital to consult in detail and follow the doctor’s instructions for standardized treatment.