Some patients are confused about the difference in postoperative pathological diagnosis after intraoperative frozen diagnosis, and even complain about the pathologist, we are here to analyze the analysis, and I think you will understand the pathologist’s plight after knowing the details: First of all, the accuracy of intraoperative frozen diagnosis itself is not high (90%-95%), that is, there is an objective misdiagnosis rate of 5%-10%, because: 1 is to take 1~2 pieces of material, very limited –Second, the quality of tissue sections after rapid freezing is poor, the images are not clear, and there are many diagnostic pitfalls; Third, the requirement to make a diagnosis in a very short time is a huge test for the pathologist, and it is inevitable that the busy thinking is not well thought out; Fourth, intraoperative diagnosis does not have special staining and immunohistochemistry and other auxiliary means; Fifth, freezing requires a very high level of pathologists -long experience, comprehensive knowledge, and a good grasp of the pitfalls. Second, many tissues and diseases are not suitable for intraoperative freezing, and surgeons do not understand and send them for examination as usual: tissues that are not suitable for freezing, such as fat, bone tissue, skin tissue, calcified tissue, edema tissue, etc., cannot be frozen at all; some diseases, such as lymphatic tissue tumors, soft tissue tumors, endocrine tumors and some diseases that require counting of split phases and adequate sampling to make a diagnosis, if these diseases are done If these diseases are frozen, the clinician is setting the pathologist up to make a mistake! Finally, it should be noted that intraoperative freezing is not a final diagnosis, but only a reference diagnosis for the surgeon, who must consider the next step in the procedure in conjunction with all other possible indicators. Currently some surgeons use freezing as a means to let the patient and the patient’s family know the pathology results earlier, which is not only against basic medical common sense, but will also lead to medical disputes!