Acinetobacter baumannii is a non-fermenting gram-negative bacillus, which is widely found in nature and belongs to conditional pathogenic bacteria. It is an important pathogen of hospital infections, mainly causing respiratory infections, but also bacteremia, urinary tract infections, secondary meningitis, surgical site infections, ventilator-associated pneumonia, etc. The rate of resistance to commonly used antibiotics has been increasing year by year, and has caused serious concern among clinicians and microbiologists. Domestic data show that Ab accounts for more than 70% of clinical isolates of immobile bacilli. the resistance rate of Ab to the third and fourth generation cephalosporins has reached 63.0%-89.9%. The resistance rate of the four aminoglycosides (amikacin, gentamicin, netilmicin, tobramycin) and ciprofloxacin reached 96.3%. The vast majority of our current strains are resistant to imipenem, meropenem, and cephalosporin. Acinetobacter baumannii Piperone/sulbactam and polymyxin B remain sensitive, but are less effective in the treatment of respiratory tract infections. Acinetobacter baumannii is the most common Gram-negative bacillus in the genus Acinetobacter and is widely found in water and soil in nature, in the hospital environment and in the human skin, respiratory tract, gastrointestinal tract and genitourinary tract, and is a conditional pathogen. It is widely distributed in the hospital environment and can survive for a long time. It is very easy to cause infection in critical patients, so it is often isolated from specimens such as blood, urine, pus and respiratory secretions of infected patients, and is second only to Pseudomonas aeruginosa in non-fermentative bacteria. The results of this investigation showed that 138 strains of A. baumannii were most frequently detected in sputum and bronchial aspirate specimens, followed by pus and secretions. The departmental distribution was most frequent in ICU, followed by patients in respiratory medicine. Infected patients are mostly elderly patients, patients with critical diseases and weak organism resistance, and patients treated with various invasive operations and long-term use of broad-spectrum antibiotics. Because the bacterium is highly resistant to moist heat ultraviolet light and chemical disinfectants, conventional disinfection can only inhibit its growth but not kill it, and patients with weak resistance or trauma may have more chances to be infected by bacteria carried from medical staff’s hands or incompletely disinfected medical devices. From the origin of 72 strains of A. baumannii, their infection sites are widely distributed, such as the respiratory system, urinary system, wounds, abdominal cavity and nervous system. Among them, respiratory system infections accounted for the majority (54.2%). Bacteroides immobilis is a genus with a high rate of hospital-acquired infections in recent years, among which infections caused by Acinetobacter baumannii should be taken seriously. The genus Acinetobacter is divided into 16 species, namely A. calcoaceticus, A. lwoffi, A. baumanii, A. haemolytius, A. junii and A. johnsonii. A. johnsonii. The epidemiology of this paragraph Immobile bacilli are widely distributed in the external environment, mainly in water bodies and soil, and easily survive in moist environments, such as bath tubs and soap boxes. The bacterium has strong adhesion, easy to adhere to all kinds of medical materials, and may become a source of storage bacteria. In addition, the bacterium also exists in the skin (25%), pharynx (7%) of healthy people, also exists in the conjunctiva, saliva, gastrointestinal tract and vaginal secretions. The source of infection can be the patient himself (endogenous infection), or it can be an infected or carrier of B. immortalis, especially medical personnel with bacteria on their hands. Transmission can be by contact and airborne transmission. In hospitals, contaminated medical equipment and the hands of A. baumannii staff are important vectors of transmission. Susceptible individuals are elderly patients, premature and newborn infants, those with surgical trauma, severe burns, tracheotomy or intubation, use of artificial ventilators, intravenous catheters and peritoneal dialysis, and those on broad-spectrum antibacterial drugs or immunosuppressive agents. The incidence of pneumonia is about 3% to 5% in those who use ventilators. Editorial paragraph clinical manifestations I. Pulmonary infection in terms of the source of infection, both exogenous and endogenous infections. The inhalation of oropharyngeal organisms is probably the main pathogenesis of endogenous infection. Fever, cough, chest pain, shortness of breath and bloody sputum are often present. The lungs may be characterized by fine woven 7-tailed pit emaciated 3-hand pneumonia, or large lobar or lamellar infiltrative shadows, and occasionally lung abscess and exudative pleurisy manifestations. Second, wound and skin infections surgical incisions, burns and wounds of trauma. All are susceptible to secondary Bacillus immobilis skin infections, or mixed infections with other bacteria. Clinical features are not significantly different from other bacterial infections. Fever is not present. Occasionally, it may manifest as cellulitis. Genitourinary system infections can cause pyelonephritis, cystitis, urethritis, vaginitis and so on. It can also present asymptomatic bacteriuria, but clinically it cannot be distinguished from other bacterial-induced infections, and its causative factors are mostly indwelling catheterization, cystostomy, etc. Bacteraemia is the most serious clinical type of Bacillus immobilis infection, with a death rate of more than 30%. Mostly secondary to other sites of infection or after intravenous catheterization, a few primary after infusion, including infusion of antibiotics, corticosteroids, anti-tumor drugs, etc.. There are fever, systemic toxicity, skin petechiae or petechiae, and hepatosplenomegaly, and in severe cases, infectious shock. A few can form plural bacteriophage bacteremia with other bacteria. V. Meningitis Meningitis mostly occurs after cranial surgery. There are manifestations of septic meningitis such as fever, headache, vomiting, neck tonicity, positive Kellogg’s sign. Laboratory: normal or increased total white blood cell count and increased neutrophil count. Sputum specimens obtained by anti-pollution sampling techniques have greater diagnostic value. Sputum smear finding gram-negative cocci can be an important clue for diagnosis. Species identification in this paragraph Biochemical identification was performed mainly based on the API-20NE system and supplemented with the necessary 5 tests. The results showed that all four immobile bacilli conformed to the general traits of the genus Immobacterium: oxidase negative, catalase positive, non-motile, indole negative, non-fermenting sugar Acinetobacter baumannii, and non-nitrate reducing. In the API-20NE system, the percent identification (%id) of 72 strains of A. baumannii was ≥ 99.0%; the %id of 15 strains of Calcium acetate was ≥ 99.0%; the %id of 3 strains of Agrobacterium was between 95.0% and 99.9%, with an average of 98.3%; the %id of 6 strains of A. loftii was between 97.0% and 99.9%, with an average of 99.4%.