Epilepsy take sodium valproate 1 ~ 4 hours to see the effect, can be used in combination with other antiepileptic drugs, to know the contraindications and adverse reactions, follow the doctor’s instructions. Sodium valproate generally has a relatively rapid onset of action, 1 to 4 hours can reach the peak concentration, began to take effect, however, some patients may be oral valproate is not particularly effective, need to be combined with other antiepileptic drugs such as carbamazepine for treatment. Sodium valproate is a broad-spectrum antiepileptic drug with anticonvulsant effects, and is mainly used to treat generalized or localized epilepsy. It is contraindicated in allergic individuals, those with liver disease or significant hepatic impairment, and those with a personal or family history of pharmacogenic jaundice. Use with caution in patients with hematologic disorders, and in pregnant and lactating women. Common adverse reactions include diarrhea, dyspepsia, nausea, vomiting, gastrointestinal cramps, and may cause changes in the menstrual cycle. Patients with epilepsy, use antiepileptic drugs under the guidance of a professional physician, do not blindly increase or decrease the dose of drugs or add drugs on their own.