Cephalosporin and antiviral drugs can be taken together. There are many kinds of antiviral drugs, such as broad-spectrum antiviral drug ribavirin, anti-DNA virus drugs such as acyclovir and ganciclovir, anti-RNA virus drugs such as antihepatitis B nucleoside drugs tenofovir and entecavir, and small molecule drugs for hepatitis C such as propofol and zebeta, etc. There are no mutual contraindications with cephalosporin antimicrobials, so They can be used together. Cephalosporins generally cannot be used together with probenecid, because probenecid can inhibit the secretion of renal tubules, which can increase the blood concentration of cephalosporins, and patients with end-stage renal disease need to be closely monitored for adverse drug reactions. There are many types of cephalosporins, including first-, second-, third-, fourth- and fifth-generation cephalosporins, each of which has a different antibacterial spectrum.