Swelling of the upper eyelids after waking up may be related to physiological factors, or it may be caused by granuloma, kidney diseases and so on. 1. Physiological factors: Drinking a lot of water before going to bed at night, consuming a lot of food with high salt content, or staying up too late may cause the metabolic circulation around the eyes to slow down, resulting in swelling of the upper eyelids after waking up. 2. Eyelid swelling: usually caused by infection at the root of the eyelash follicle at the edge of the eyelid, which can form a red, painful lump locally in the eyelid, and may cause swelling of the upper eyelid after waking up, due to the rapid onset of the disease, the eyelid will soon appear to be swollen. 3. Kidney disease: common in chronic nephritis, renal insufficiency, etc., resulting in renal dysfunction, resulting in a decrease in renal filtration rate, resulting in the accumulation of water in the body in the interstices of the tissues, you may wake up with swelling of the upper eyelids. Swelling of the upper eyelids after waking up may also be caused by other reasons, if the symptoms continue to be unable to relieve, or there are other symptoms of discomfort, you should go to the hospital in a timely manner, to confirm the cause of the diagnosis, and then follow the doctor’s instructions for treatment.