Sweat blister refers to the appearance of a large number of rice-grain blisters on the palms and lateral edges of the hands due to poor perspiration in the hot summer months, along with erythema and papules, accompanied by itching, and in severe cases, peeling skin, so the specific treatment into the following: first, the appearance of mild itching, accompanied by a small number of rice-grain blisters, you can apply a mixture of mometasone furoate cream and urea vitamin E cream for external use. Secondly, a large number of rice-like blisters with severe itching appeared, you can take oral compound glycopyrrolate tablets and vitamin B6, and also oral imipramine extended-release tablets, and topical medication can be applied with a mixture of compound flumethasone ointment and skin cream. After the above treatment, the patient does not see relief and can be treated with topical Botox. Therefore, for the medication treatment of sweat pimples, it is necessary to go to a regular hospital under the guidance of a dermatologist.