Rib pain in advanced stage of lung cancer can be relieved by analgesic drugs such as ibuprofen extended-release capsules, clonoxicam tablets, colestipol tablets, etc. It is recommended that patients adopt radiotherapy and chemotherapy for treatment as soon as possible. Most of the rib pain in advanced stage of lung cancer is caused by spreading and metastasis of lung cancer cells. Patients can use drugs such as ibuprofen extended-release capsule, clonoxicam tablets, colestipol tablets and other drugs for analgesic relief, but the use of drugs must be taken under the guidance of doctor. Rib pain in advanced stage of lung cancer is very likely to have spread and metastasized, and the patient’s life may be in danger at any time, so it should be treated as soon as possible, and it can be considered to carry out local radiotherapy at the metastasis of ribs, which can kill cancer cells in the body of the patient. Therefore, once the rib pain of lung cancer occurs, it is suggested that patients should go to the hospital to take CT scan in order to choose the suitable treatment for themselves, and the medication must be taken according to the doctor’s prescription.