Headaches caused by sinusitis should be treated with medication, such as nasal sprays and antibiotic drugs, supplemented by saline nasal cleansing. If medication is ineffective, surgical treatment can be taken. 1. When sinusitis strikes, it is often accompanied by nasal congestion, runny nose, cough, headache and other symptoms. The location of the headache varies due to the different parts of the body where the inflammatory infection occurs. For treatment, you should take antibiotic medication as prescribed by your doctor, such as Amoxicillin Clavulanate Potassium Tablets, Cefaclor Extended-Release Tablets, etc., as well as Budesonide Spray or Hydroxymetazoline Hydrochloride Spray. 2. In addition to medication, you can also use saline to clean the nasal cavity, which can relieve nasal discomfort as well as headache symptoms. 3. If sinusitis causes headache, you can take endoscopic sinus surgery if there is no relief from long time non-surgical treatment. If sinusitis causes headache, it is recommended to go to a regular hospital, under the guidance of a professional doctor to standardize the treatment, do not blindly use their own medication, which can better control the condition, headache relief.