It is possible that long-term survival can be achieved after a cure for M4 leukemia, and five years of progression-free survival is often used clinically as a criterion for cure. M4 leukemia is also called acute granulomonocytic leukemia, patients with this type of disease, if you do not get active treatment from the doctor, the patient’s survival time will be relatively short, can be in about six months due to severe bleeding, anemia and infections and other life-threatening. However, with active treatment, patients can achieve long-term survival. Specific drugs include cytarabine and Zoerythromycin. The cause of acute granulomonocytic leukemia is due to the lesion of hematopoietic stem cells in the bone marrow, resulting in a large number of leukemia cells proliferating in the bone marrow and hindering the normal hematopoietic function of the bone marrow, resulting in a decrease in the number of blood cells in the whole blood, as well as infections, anemia, and hemorrhage, which can be even life-threatening. If the patient’s disease is effectively treated and there is no relapse within five years, long-term survival can be expected. Acute granulomonocytic leukemia patients need to go to the hospital to receive regular treatment to avoid adverse effects.