Resistance may disappear in six months to a year, or it may last a lifetime. The duration of resistance varies from person to person and is influenced by a number of factors, such as the time the person has been taking the drug, his or her own immunity, and the severity of the disease. Some people’s resistance may disappear within half a year, but some people have lifelong resistance, for example, some tumor patients have lifelong resistance to tumor drugs. For example, some tumor patients have lifelong resistance to tumor drugs, while some clinically used antibiotics are generally not lifelong resistant, and the resistance may gradually disappear over time. Therefore, patients must take all kinds of drugs under the guidance of doctors and avoid taking them without authorization. Communicate with your doctor about the timing and efficacy of your medication so that he or she can adjust the medication to minimize the emergence of drug resistance. During the medication period, patients should also adopt a good lifestyle, ensure sufficient sleep and healthy eating habits.