The blisters on the hands can be treated by local disinfection, picking the blisters or applying medication. 1. Local disinfection: If the blisters on your hands are small, you can apply iodine to disinfect them, and they will be absorbed by themselves with the growth of time, and you should pay attention to avoiding friction and preventing infections. 2. Puncture the blisters: If the blisters are relatively large and the blisters are not broken, you can use a sterilized syringe to puncture the blisters, apply iodine povidone to sterilize the blisters, and cover the wounds with adhesive tape or dressings. 3. Apply drugs: after the pus from the blister is discharged, you can use iodine povidone or disinfectant water to disinfect it, and then apply erythromycin ointment locally to avoid infection and promote the healing of the blister. Patients should pay attention to local hygiene to avoid wound infection, if you need to use drugs, must be strictly in accordance with the doctor’s instructions to use, not indiscriminate use, so as not to induce adverse consequences.