High white blood cell and red blood cell counts are commonly seen in the following diseases: 1. Chronic granulocytic leukemia, which causes increased white blood cell and red blood cell counts. For the treatment of this disease, the first-line treatment drugs are currently tyrosine kinase inhibitors, and commonly used drugs include imatinib, dasatinib, and nilotinib. If patients with chronic granulocytic leukemia can receive timely, standardized treatment, most patients can get long-term remission, and some can even be cured. 2, seen in the early stages of myelofibrosis, there will also be elevated white blood cell and red blood cell counts, the treatment of the disease is based on drug therapy, you can choose Conradon, testosterone propionate, alpha-interferon, prednisone for treatment. 3, true erythrocytosis The disease can be treated with hydroxyurea, cyclophosphamide, and intravenous bloodletting.