Metastasis is one of the biological characteristics of malignant tumors, and also makes many patients and family members talk about it. According to statistics, more than half of the patients with malignant tumors will have bone metastasis, and their metastasis sites are mostly found in the spine, pelvis, etc. When bone metastasis occurs in malignant tumors, the most common symptom of patients is pain and soreness in the corresponding parts, and this feeling is more obvious at night, and if fractures occur, they will have corresponding dysfunction according to the fracture site. If fracture occurs, corresponding functional impairment will occur according to the fracture site, and in serious cases, paralysis will occur, which has a great impact on the quality of life of cancer patients, so how to detect bone metastasis early and early intervention and treatment is more important. For patients with a history of malignant tumors, especially those with adenocarcinoma, such as prostate cancer, breast cancer, thyroid cancer, lung cancer, etc., they should be alert to pain and soreness without obvious reasons and undergo relevant examinations as soon as possible. Do not blindly carry out physical therapy, especially strong massage, otherwise it may prompt the occurrence of fracture. Several misconceptions: Misconceptions: back and leg pain, back pain and active pain are considered as sprains and cold; wrong treatment: physical therapy, plasters, acupuncture, cupping, independent painkillers, and even massage; further examination will be done only when all methods are exhausted and the pain is obviously aggravated or the bone pain is unbearable, and at this time, multiple bone metastases have occurred. A few points of caution: soreness, dull pain unexplained bone pain, impaired mobility intermittent and progressive aggravation predominantly nocturnal pain limited pain with clear pressure points history of malignancy, especially patients with pathological type of adenocarcinoma some tests to understand bone metastases: X-ray: to understand the overall contour of the bones, not suitable for early diagnosis (cost$130) CT examination: to understand the destruction of bones by metastases and to judge the degree, but it is not as good as MRI for local subtle display (cost 250 RMB) . Magnetic resonance imaging (MRI): fine observation of the degree of invasion of bones and surrounding tissues, with diagnostic accuracy of more than 90%, but the scope of one examination is limited (cost$580). Bone scan (ECT): one examination, can observe the whole body skeleton, find the approximate location of the lesion, general overview, but local observation ability is poor (cost$795). PET/CT examination: it can observe small lesions comprehensively from head to toe and pinpoint the location, which is expensive (cost$7,000). Bone aspiration biopsy: it can clarify the pathological type of bone metastasis cancer, which is an invasive examination and generally not preferred.