Perinatal cardiomyopathy is not recommended for another pregnancy. Perinatal cardiomyopathy is a heart disease with no previous heart disease that occurs at the end of pregnancy or within five months after delivery with myocardial damage as the main manifestation, and other heart diseases must be excluded for the diagnosis. The etiology of perinatal cardiomyopathy is unknown and may be the result of a combination of factors, mainly related to advanced age, multiple births, multiple fetuses, viral infections, immunity, and other factors. Clinical manifestations can include chest tightness, dyspnea and other manifestations of heart failure and arrhythmias. Because the object of damage in perinatal cardiomyopathy is the heart muscle, the patient’s state is inherently unstable, so another pregnancy is not recommended. Patients who become pregnant again may have a more severe disease than the first time, while perinatal cardiomyopathy is treated with anti-heart failure drugs, such as Benadryl and diuretics, which are more harmful to the fetus and may cause fetal malformations. Because many perinatal cardiomyopathies have a better prognosis, if evaluated, another pregnancy can occur, but it is important to note that the chances of another pregnancy with another perinatal cardiomyopathy are higher than in the general population. Therefore, for older women with perinatal cardiomyopathy, it is clinically recommended to try not to become pregnant again, even if the cardiomyopathy is recovered.