Reporting of gastric sinus IIa+IIc is mostly suggestive of mucosal lesions of the gastric sinus, but does not exclude the possibility of malignant lesions. Gastric sinus IIa+IIc is an endoscopic finding that is commonly used to characterize the morphology of lesions in gastrointestinal diseases. Among these, type II is superficial, subdivided into type IIa as a superficial elevation and type IIc as a superficial depression. Thus, type IIa+IIc refers to superficial lesions with depressions as well as elevations, mostly suggestive of submucosal inflammation of the gastric sinuses. However, it should be noted that type IIa+IIc lesions are more common in patients with early gastric cancer, and the most favorable sites are in the gastric sinus and body of the stomach, while other sites are less common. Therefore, the presence of gastric sinus IIa+IIc cannot exclude the possibility of gastric cancer. For patients with gastric sinus IIa+IIc, they should consult doctor in time for further relevant examination to make a clear diagnosis. In daily life, patients should pay attention to their diet, eat regularly, avoid overeating, and should not consume too spicy and stimulating food.