Normally, normal human plasma or serum creatinine ranges from 44 to 97 umol/L in women and 53 to 106 umol/L in men.
Creatinine comes primarily as a result of metabolites from muscle. Since creatinine passes freely through the glomeruli, the tubules essentially never absorb creatinine. So creatinine can be used to reflect glomerular filtration function. However, due to the different reagents as well as instruments used in different laboratories, the standardized values may vary.
When blood creatinine is elevated, it suggests a decrease in glomerular filtration function, which is commonly seen in various glomerular diseases, acute renal failure, or secondary glomerular diseases. Decrease in serum creatinine is commonly seen in patients who are thin or have little exercise, which is usually not too worrying and does not require special treatment.
When there is an abnormality in the experimental examination, it is recommended to follow the doctor’s instructions for further relevant examinations, to clarify the cause with the help of the doctor, and to carry out standardized treatment.