Dosophylline and aminophylline are not recommended to be taken together, they belong to the same type of drugs, similar pharmacological effects, should be used in accordance with medical advice. Dosophylline is a derivative of methylxanthine, belonging to the bronchodilator, can inhibit smooth muscle cells, relaxation of smooth muscle, to inhibit the role of asthma. Used for wheezing chronic bronchitis, bronchial asthma and other bronchospasm caused by dyspnea. Adverse reactions to doxophylline include sinus tachycardia, palpitations (rapid heartbeat, often accompanied by panic), epigastric discomfort, nausea, nausea (poor appetite), vomiting, insomnia, and euphoria. The drug is contraindicated in people who are allergic to the product and in people with acute myocardial infarction. Aminophylline also belongs to the derivatives of methylxanthine, which can directly relax the smooth muscles of the respiratory tract. It can be used to relieve wheezing symptoms such as wheezing bronchitis, bronchial asthma, and obstructive emphysema; it is also used for asthma caused by cardiogenic pulmonary edema. Adverse effects of aminophylline include insomnia, tachycardia, nausea, vomiting, agitation, cardiac arrhythmia, and in severe cases, respiratory and cardiac arrest. The drug is contraindicated in people with active peptic ulcers, hypersensitivity to the product, and uncontrolled convulsive disorders. Therefore, doxophylline and aminophylline belong to the same type of drugs with similar pharmacological mechanisms, and are not recommended to be used together, and should be standardized under the guidance of a doctor.