Inflammation on both sides of the penis may be associated with causes such as glans circumcision, allergic dermatitis, and sexually transmitted diseases, which need to be further differentiated and diagnosed by a doctor. 1. Circumcision and glansitis: it can be manifested as swelling and inflammatory reaction on both sides of the penis, with symptoms such as redness, swelling, itching and pain. 2. Allergic dermatitis: if contact with condoms and other allergenic substances, can cause the body to develop an abnormal immune response, manifested in inflammatory reactions on both sides of the penis. 3. Sexually transmitted diseases (STDs): If the penis is infected with gonococcus, it can cause inflammation of the penis. It is recommended that people with inflammation on both sides of the penis go to the hospital in time to clarify the cause of the disease and carry out standardized treatment under the guidance of the doctor, so as not to delay the condition.