Anemia in chronic lymphocytic leukemia drug treatment is mainly for leukemia treatment, common drugs include interferon, chemical drugs, targeted drugs and so on. Anemia is mainly symptomatic treatment, if the anemia is serious, blood transfusion treatment. 1. Chronic lymphocytic leukemia manifests as lymphocyte proliferation and is a kind of tumor. It progresses slowly. In the early stage, if there are only increased lymphocytes and enlarged lymph nodes, no special treatment can be done and close observation can be carried out. Once symptoms such as anemia, platelet drop, recurrent infections, fever and significant weight loss appear, treatment is needed. 2. Leukemia drug therapy should be chosen according to one’s own situation, often a variety of drugs are used in combination, and different people have different combined drug programs. Commonly used drugs include interferon, chemical drugs such as fludarabine, cyclophosphamide, bendamustine, hormone methylprednisolone, etc., and targeted drugs such as rituximab and ibrutinib. 3. For anemia symptoms, the main symptomatic treatment, if the anemia is mild, usually can intake of iron-rich food; if it is more serious, such as hemoglobin <60g / L, then the need for blood transfusion treatment. Anemia in chronic lymphocytic leukemia is recommended to go to the hospital in time for treatment, and choose the appropriate medication plan under the guidance of the doctor, and in general, the condition is mostly under good control. All the above drugs should be used under the guidance of a doctor.