Yellow eyes include physiological and pathological, not blindly use eye drops, need to be treated according to the cause, such as liver insufficiency feasible liver protection treatment. With age, due to long-term contact with the external environment, the transparency of the conjunctiva decreases. Physiological color changes can occur, look yellow or even with brown, this physiological phenomenon usually do not need to be treated. Some pathologic factors such as liver insufficiency, choledocholithiasis, and other diseases of the hepatobiliary system can lead to jaundice and yellowing of the eyes. Hepatic insufficiency can be treated according to the doctor’s advice on the cause of the disease and the corresponding liver protection treatment, commonly used drugs include reduced glutathione, adenosylmethionine and so on. Choledocholithiasis can be treated with surgical removal of stones. There are many causes of yellowing of the eyes, it is recommended to consult a doctor in time to clarify the cause, and then follow the doctor’s instructions for treatment, under the guidance of the doctor for the use of medication.