The hazards of misalignment of teeth bite are sensitivity symptoms, mouth restriction, loose teeth, dental diseases, etc., as follows: First, sensitivity symptoms: misalignment of teeth bite can cause excessive wear of the tooth surface, enamel disappears, exposed dentin will be sensitive to hot, cold, sweet and sour symptoms, severe cases can make the clinical crown short, loss of anatomical form, while the vertical distance is lowered. Restriction of mouth opening: misalignment of teeth occlusion can form jaw interference or early contact, inducing temporomandibular joint dysfunction, mouth opening restriction, joint popping and other symptoms. Third, loose teeth: misalignment of teeth can occur frequently bite trauma, so that the roots of the teeth gradually thinning, periodontal tissues began to atrophy, and even cause loose teeth, chewing weakness. Fourth, cause dental disease: misaligned teeth will form a triangular gap with the neighboring teeth, easy to embedded food fibers, triggering caries, periodontal disease and so on.