Tacrolimus ointment, follow the doctor’s instructions to regulate the use of medication will not make vitiligo aggravated, if large doses or long-term use, may produce adverse drug reactions, which will make vitiligo aggravated.
Vitiligo is a common pigmented skin disease, manifested as limited or generalized complete loss of skin and mucous membrane pigmentation. Vitiligo patients, topical application of tacrolimus ointment can effectively inhibit the local production of inflammatory reactions, but also stimulate tyrosinase activity, promote the proliferation of melanocytes, so as to achieve the role of restoring melanocytes.
If large doses or long-term use of tacrolimus ointment in the treatment of vitiligo, it may cause patients to develop photosensitivity reactions, seborrheic dermatitis, skin discoloration, skin cancer and other adverse reactions, which in turn aggravate the symptoms of vitiligo. Therefore, when using tacrolimus ointment, it is necessary to follow the doctor’s instructions to use according to the dose.
If the patient’s vitiligo symptoms are serious, or the symptoms persist and have not improved, it is recommended to go to the hospital in time for treatment. Tacrolimus ointment should be used in accordance with the doctor’s instructions, do not self-medication.