hmg-coa, stands for hydroxymethylglutaric acid monoacyl coenzyme a. Hydroxymethylglutaric acid monoacyl coenzyme a reductase inhibitor. This refers to lipid-lowering drugs in the statin class. The representative drugs of this class are simvastatin, pravastatin, resevastatin, and atorvastatin. These drugs are widely used in clinical practice, mainly for lowering LDL and total cholesterol, and also for raising HDL cholesterol. In addition to its lipid-lowering effect, it can also stabilize plaque, improve vascular endothelial function, and have anti-inflammatory effects. It is a secondary prevention drug for patients with coronary artery disease and angina pectoris. These drugs are recommended to be taken by patients for a long time and for life.