Tricuspid regurgitation may be asymptomatic in the early stages, but with the progression of the disease, it may cause blood stasis in the circulation. Symptoms may include fatigue, heart failure, abdominal pain and distension, nausea and vomiting, jugular vein distension, and edema of both lower limbs. Tricuspid regurgitation is usually caused by tricuspid valve insufficiency. Tricuspid regurgitation occurs during systole of the right ventricle, and tricuspid valve insufficiency causes the blood from the right ventricle to flow back into the right atrium, resulting in stasis of blood in the circulation, which cannot flow into the heart, and thus causing obstruction of peripheral blood return, and obstruction of the internal circulation. Tricuspid regurgitation may have no obvious symptoms in mild cases. As the disease progresses, weakness, shortness of breath, palpitation, etc., and in severe cases, heart failure and shock may occur. If the blood return to the liver is obstructed, it may cause abdominal distension and pain, etc.; stasis of blood in the gastrointestinal tract may cause nausea and vomiting, etc.; obstruction of the blood return to the neck may cause jugular vein distension, etc.; and obstruction of the blood return to lower limbs may cause double lower extremity edema. Tricuspid regurgitation may also have other symptoms, and it is recommended to seek timely medical treatment to avoid adverse effects.