The side effects of antiviral drugs for hepatitis B mainly include interferon, entecavir and tenofovir, etc. The side effects are as follows: 1. Side effects of interferon: fever as the main side effect, flu-like syndrome reaction and bone marrow suppression side effects, the appearance of platelets and white blood cell reduction, and also induce some immune system diseases, such as thyroiditis, autoimmune liver disease, etc. The application of interferon should be checked regularly for blood routine. Observe the changes in white blood cells and platelets; 2. Side effects of entecavir: dizziness, drowsiness, insomnia, etc.; 3. Adverse reactions of tenofovir: gastrointestinal irritation and nephrotoxic reactions can occur, long-term use of tenofovir can also have an effect on blood phosphorus, resulting in hypophosphatemia, so for the elderly, osteoporosis patients should be used with caution, application of tenofovir often carry out Renal function check.