Creatine kinase isoenzyme (CK-MB) 33 is elevated. By electrophoresis, the normal value of CK-MB is less than 0.05; by enzyme rate assay (37℃), the normal value of CK-MB is 0-18 U/L. Therefore, creatine kinase isoenzyme 33 is elevated, which often indicates that there are myocardial injuries, skeletal muscle injuries and malignant tumors and other possibilities. 1. Myocardial injury: elevated creatine kinase isoenzyme is commonly found in myocardial injury, such as early acute myocardial infarction, myocarditis and so on, when myocardial cells appear damaging changes, due to the necrosis of myocardial cells in the myocardial cells of the enzyme will be released into the bloodstream, resulting in a substantial increase in the value of CK-MB in the blood. 2. Skeletal muscle injury: When skeletal muscle injury occurs, the activity of creatine kinase isoenzyme CK-MB will increase, suggesting the possibility of skeletal muscle injury. 3. Malignant tumors: High activity of CK-MB can also be detected in the serum of patients with esophageal cancer, gastric cancer, liver cancer and so on. Cancer patients may cause muscle damage, which will lead to elevated creatine kinase. Therefore, patients with elevated creatine kinase isoenzymes should go to the hospital in time, and undergo relevant tests to determine the diagnosis, and under the guidance of the doctor, treatment should be carried out.