Magnesium sulfate poisoning is the application of excessive magnesium sulfate, resulting in the body magnesium ion concentration is too high caused by poisoning, the treatment of the following four points: 1, immediately stop the drug, the application of symptomatic detoxification drugs, such as 10% calcium gluconate given 20-30ml intravenous injection, 5-10 minutes apart to observe the situation, if the patient’s symptoms do not ease, but also continue to apply calcium gluconate injection 20ml. and closely monitor Patient’s blood pressure, heart rate, oxygen saturation, pulse and body temperature, if abnormalities must be immediately symptomatic treatment. 2, can apply symptomatic other drugs such as diuretics, can apply hydrochlorothiazide and furosemide to promote the excretion of magnesium sulfate from the urine. 3, if the patient is obviously poisoned, in the hospital with conditions also feasible blood purification treatment. 4, symptomatic treatment.