Multiple nodules in the upper lobe of the right lung may be caused by benign or malignant nodules. 1. Benign nodules: If lung imaging suggests that there are multiple nodules in the upper lobe of the right lung, and the nodule foci are relatively smooth, round or round-like, and solid, it is generally considered to be a benign nodule caused by lung infection, benign lung tumor, and so on. Tuberculosis: If tuberculosis causes multiple nodules in the upper lobe of the right lung, they are proliferative and mostly benign. If the nodules continue to grow and become larger, and short burrs, lobular signs, cavities, etc. appear, we should be alert to the possibility of malignant changes. 2. Malignant nodules: multiple nodules in the upper lobe of the right lung may also be malignant nodules caused by lung cancer and other diseases, accompanied by burr, lobulation sign, vacuole sign and vascular sign. In addition, metastatic tumors of malignant tumors in distant organs may also manifest as multiple nodules. In case of multiple nodules in the upper lobe of the right lung, it is recommended to cooperate with professional doctors to complete the follow-up examination as soon as possible to clarify the nature of the nodules and the type of the disease, and to formulate the next step of the treatment plan as soon as possible.