Tuberous sclerosis is an inherited skin disease, usually caused by autosomal dominant inheritance. The main manifestations are angiofibromas of the face, epilepsy, and mental retardation. There are usually four characteristic lesions, the first is angiofibromas of the face, most of which are located in the nasolabial folds or on both sides of the nose, usually occurring sporadically, and may be yellowish or reddish in color, accompanied by dilated capillary papules. There are also perinail fibromas, which appear as bright red, smooth, tough, scar-like lesions around the nails. Others include sharkskin-like plaques or lobular depigmentation. Treatment is usually symptomatic, such as topical ointments if there is itching, but there is no specific therapy.