Currently there is no specific drug for prolonged cough, prolonged cough should be based on the cause of targeted treatment. Long-term cough is a relatively common clinical symptoms, generally associated with tuberculosis, chronic bronchitis and other causes, there is no clinically effective drugs for prolonged cough, must be based on the cause of the standardized treatment, in order to alleviate the clinical symptoms. Tuberculosis caused by chronic cough can be treated with anti-tuberculosis drugs, such as rifampicin, isoniazid; chronic bronchitis caused by chronic cough need to choose the appropriate anti-infective drugs for treatment, such as amoxicillin, levofloxacin, etc., and discretionary application of cough suppressants, such as Pentoxyverine, dextromethorphan. Prolonged cough may also be caused by other causes, such as lung tumors, chronic obstructive pulmonary disease, should seek medical attention to clarify the cause, and standardized treatment, so as to avoid further aggravation of the condition.