Erythromycin Isotretinoin Gel removes blackheads, which are a manifestation of acne. Other medications used to treat blackheads include viamin and erythromycin, and physical therapy is also available. Erythromycin Isotretinoin Gel is a compound that can be used to treat mild to moderate cases of unusual acne. Since blackheads are a manifestation of unusual acne, Erythromycin Isotretinoin Gel can remove them. In addition to treating unusual acne, this medication is also used clinically to treat inflammatory and non-inflammatory skin lesions. Erythema and peeling may occur at the site of application when using this medication, and it is contraindicated for people with known hypersensitivity to any of the ingredients in this product. For patients with moderate to moderately severe acne who have failed conventional treatments, topical retinoids such as vilamate and potassium 13-cisvirate are also required as prescribed by the doctor. In case of co-infection, antibiotic drugs such as erythromycin and chloramphenicol need to be applied as prescribed by the doctor. In addition to this, physical measures such as photodynamic therapy and laser therapy can also be used to treat acne. To sum up, for people with blackheads, erythromycin isotretinoin gel needs to be applied under the guidance of a doctor, and should not be used without authorization.